350818-67-6

350818-67-6 structure

Name: Rimantadine-d4 hydrochloride
Chemical Name: rimantadine-d4 hcl (ethyl-d4)
CAS Number: 350818-67-6
Molecular Formula: C₁₂H₁₈ClD₄N
Molecular Weight: 219.78700
Catalog: Signaling Pathways Anti-infection Influenza Virus
Create Date: 2018-02-26 08:00:00
Modify Date: 2024-01-04 00:14:30
Rimantadine-d4 hydrochloride is the deuterium labeled Rimantadine hydrochloride. Rimantadine hydrochloride is an anti-influenza virus agent[1][2].

Name	rimantadine-d4 hcl (ethyl-d4)
Synonyms	RiMantadine-d4 HCl 1-ADAMANTYLETHYLAMINE HCl

Description	Rimantadine-d4 hydrochloride is the deuterium labeled Rimantadine hydrochloride. Rimantadine hydrochloride is an anti-influenza virus agent[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Tominack, R.L. and F.G. Hayden, Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections. Infect Dis Clin North Am, 1987. 1(2): p. 459-78. [3]. Hall, C.B., et al., Children with influenza A infection: treatment with rimantadine. Pediatrics, 1987. 80(2): p. 275-82.