80755-67-5
80755-67-5 structure
- Name: m-PEG5-Tos
- Chemical Name: 2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethanol,4-methylbenzenesulfonic acid
- CAS Number: 80755-67-5
- Molecular Formula: C18H30O8S
- Molecular Weight: 424.50600
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-04-30 19:49:40
- Modify Date: 2024-01-10 18:05:51
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m-PEG5-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-c). m-PEG5-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].
| Name | 2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethanol,4-methylbenzenesulfonic acid |
|---|---|
| Synonyms |
2,5,8,11,14-Pentaoxahexadecan-16-ol,4-methylbenzenesulfonate
pentaethylene glycol mono methyl ether tosylate pentaethyleneglycol monomethyl ether monotosylate pentaethyleneglycol momomethyl ether tosylate 14-methoxy-3,6,9,12-tetraoxatetradecyl toluene-p-sulfonate TsO(CH2CH2O)5Me |
| Description | m-PEG5-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-c). m-PEG5-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Molecular Formula | C18H30O8S |
|---|---|
| Molecular Weight | 424.50600 |
| Exact Mass | 424.17700 |
| PSA | 129.13000 |
| LogP | 2.01400 |
| Storage condition | 2-8°C |
| Precursor 6 | |
|---|---|
| DownStream 1 | |
