1223-36-5

1223-36-5 structure

Name: 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide
Chemical Name: 2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide
CAS Number: 1223-36-5
Molecular Formula: C₁₄H₂₁ClN₂O₂
Molecular Weight: 284.78200
Create Date: 2018-06-01 08:00:00
Modify Date: 2024-01-09 16:30:21

Name	2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide
Synonyms	ANP 246 Clofexamide EINECS 214-951-6 IEM 455 Amichlophene Chlofexamide NP 246 4-Chlorphenoxyessigsaeure-<2-diethylaminoethylamid>

Density	1.12g/cm3
Boiling Point	449.7ºC at 760 mmHg
Molecular Formula	C₁₄H₂₁ClN₂O₂
Molecular Weight	284.78200
Flash Point	225.8ºC
Exact Mass	284.12900
PSA	41.57000
LogP	2.56770
Vapour Pressure	2.81E-08mmHg at 25°C
Index of Refraction	1.522

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AB5822500

CHEMICAL NAME :: Acetamide, 2-(p-chlorophenoxy)-N-(2-(diethylamino)ethyl)-

CAS REGISTRY NUMBER :: 1223-36-5

LAST UPDATED :: 199712

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C14-H21-Cl-N2-O2

MOLECULAR WEIGHT :: 284.82

WISWESSER LINE NOTATION :: GR DO1VM2N2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1040 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 17,935,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1200 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 1,444,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 290 mg/kg

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 38,154,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 145 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #2702M

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 167 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMXXAJ French Medicament Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Discontinued. Volume(issue)/page/year: #2702M

HS Code	2924299090

100-36-7

4122-68-3

1223-36-5

Literature: Thuillier,G.; Rumpf,P. Bulletin de la Societe Chimique de France, 1960 , p. 1786 - 1794

122-88-3

1223-36-5

Literature: Thuillier,G.; Rumpf,P. Bulletin de la Societe Chimique de France, 1960 , p. 1786 - 1794

14426-42-7

100-36-7

1223-36-5

Literature: Thuillie,G. Chimica Therapeutica, 1966 , vol. 1, p. 82 - 86

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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