102039-86-1

102039-86-1 structure

Name: Cephaloridine hydrate
Chemical Name: (6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate,hydrate
CAS Number: 102039-86-1
Molecular Formula: C₁₉H₁₉N₃O₅S₂
Molecular Weight: 433.50100
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2017-06-21 08:00:48
Modify Date: 2024-01-16 22:35:19
Cephaloridine hydrate is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity[1][2].

Name	(6R,7R)-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate,hydrate
Synonyms	Cephaloridine hydrate

Description	Cephaloridine hydrate is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Cephaloridine hydrate 可抑制金黄色葡萄球菌青霉素敏感菌株、青霉素耐药菌株、化脓性链球菌、肺炎链球菌、白喉棒状杆菌等，MIC 为 0.05-1 μg/mL[1]。
In Vivo	Cephaloridine hydrate (50-500 mg/kg; 肌肉注射) 在兔和猴子中表现出剂量相关的肾毒性[2]。
References	[1]. P. W. Muggleton, et al. Laboratory Evaluation of a New Antibiotic-Cephaloridine (Ceporin). Br Med J. 1964 Nov 14;2(5419):1234-7. [2]. Perkins RL, et al. Cephaloridine and cephalothin: comparative studies of potential nephrotoxicity. J Lab Clin Med. 1968 Jan;71(1):75-84.