Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Benzotript
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39544-74-6

39544-74-6 structure

39544-74-6 structure

Name: benzotript
Chemical Name: benzotript
CAS Number: 39544-74-6
Molecular Formula: C₁₈H₁₅ClN₂O₃
Molecular Weight: 342.78
Catalog: Biochemical Amino acids and their derivatives Tryptophan derivatives
Create Date: 2019-02-16 08:08:13
Modify Date: 2025-08-24 19:41:21
Benzotript (Benzotriptum) is a cholecystokinin-receptor (CCK) and gastrin receptor antagonist. Benzotript shows antiproliferative effects in human colon carcinoma cell lines[1].

Name	benzotript
Synonyms	N-carbamothioyl-4-chloro-benzamide EINECS 254-500-0 N-p-Chlorbenzoyl-thioharnstoff (4-chloro-benzoyl)-thiourea N-p-chlorobenzoyl-L-tryptophane N-(4-chlorobenzoyl)-L-tryptophan

Description	Benzotript (Benzotriptum) is a cholecystokinin-receptor (CCK) and gastrin receptor antagonist. Benzotript shows antiproliferative effects in human colon carcinoma cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Cholecystokinin Receptor Research Areas >> Inflammation/Immunology
References	[1]. N M Hoosein, et al. Antiproliferative effects of gastrin receptor antagonists and antibodies to gastrin on human colon carcinoma cell lines. Cancer Res. 1988 Dec 15;48(24 Pt 1):7179-83. [2]. C Niederau, et al. Caerulein-induced acute necrotizing pancreatitis in mice: protective effects of proglumide, benzotript, and secretin. Gastroenterology. 1985 May;88(5 Pt 1):1192-204.

Boiling Point	643.7ºC at 760 mmHg
Molecular Formula	C₁₈H₁₅ClN₂O₃
Molecular Weight	342.78
Flash Point	343.1ºC
Exact Mass	342.07700
PSA	82.19000
LogP	3.63790

HS Code	2933990090

74-11-3 structure

74-11-3

~%

39544-74-6 structure

39544-74-6

Literature: Burdick, Daniel J.; Marsters Jr., James C.; Aliagas-Martin, Ignacio; Stanley, Mark; Beresini, Maureen; Clark, Kevin; McDowell, Robert S.; Gadek, Thomas R. Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 9 p. 2055 - 2059

122-01-0 structure

122-01-0

73-22-3 structure

73-22-3

~%

39544-74-6 structure

39544-74-6

Literature: Hwang, Tsong-Long; Hung, Chih-Hao; Hsu, Ching-Yun; Huang, Yin-Ting; Tsai, Yu-Chi; Hsieh, Pei-Wen Organic and Biomolecular Chemistry, 2013 , vol. 11, # 22 p. 3742 - 3755

Precursor 3
74-11-3 122-01-0 73-22-3
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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