259225-40-6

259225-40-6 structure

Name: (4,5,5,5,5',5',5'-2H7)Leucine
Chemical Name: dl-leucine-4,5,5,5,6,6,6-d7
CAS Number: 259225-40-6
Molecular Formula: C₆H₆D₇NO₂
Molecular Weight: 138.22
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-03-13 08:00:00
Modify Date: 2024-01-09 17:08:08
(±)-Leucine-d7 is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%[1].

Name	dl-leucine-4,5,5,5,6,6,6-d7
Synonyms	Leucine-4,5,5,5,5',5',5'-d (4,5,5,5,5',5',5'-H)Leucine

Description	(±)-Leucine-d7 is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Hendricks DE, et, al. Attractiveness of tobacco budworm females altered by oral chemosterilants and dietary additives. Journal of Chemical Ecology. 1977 Mar; 127-131.