Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Dimethyl morpholinophosphoramidate.
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

597-25-1

597-25-1 structure

Name: Dimethyl morpholinophosphoramidate.
Chemical Name: 4-dimethoxyphosphorylmorpholine
CAS Number: 597-25-1
Molecular Formula: C₆H₁₄NO₄P
Molecular Weight: 195.15300
Create Date: 2017-02-06 06:13:20
Modify Date: 2025-08-25 10:22:22

Name	4-dimethoxyphosphorylmorpholine
Synonyms	Dimethyl 4-morpholinylphosphonate HC 1717 Morpholino-phosphonsaeure-dimethylester N,N-oxydiethylene-O,O-dimethylphosphoramidate Dimethylmorpholinophosphonate morpholin-4-yl-phosphonic acid dimethyl ester Orthophosphorsaeure-dimethylester-morpholinid DIMETHYL MORPHOLINOPHOSPHORAMIDATE Dimethyl morpholino phosphoroamidite dimethyl morpholin-4-ylphosphonate

Density	1.21g/cm3
Boiling Point	246.8ºC at 760 mmHg
Molecular Formula	C₆H₁₄NO₄P
Molecular Weight	195.15300
Flash Point	103.1ºC
Exact Mass	195.06600
PSA	57.81000
LogP	0.65740
Index of Refraction	1.454

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SZ9660000

CHEMICAL NAME :: Phosphonic acid, morpholino-, dimethyl ester

CAS REGISTRY NUMBER :: 597-25-1

BEILSTEIN REFERENCE NO. :: 0141995

LAST UPDATED :: 199710

DATA ITEMS CITED :: 22

MOLECULAR FORMULA :: C6-H14-N-O4-P

MOLECULAR WEIGHT :: 195.18

WISWESSER LINE NOTATION :: T6N DOTJ APO&O1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5910 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2370 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 347 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - cyanosis

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 35 gm/kg/14D-I

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 52 gm/kg/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 28 gm/kg/14D-I

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 26 gm/kg/13W-I

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 309 gm/kg/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Blood - leukemia

TYPE OF TEST :: Specific locus test

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 3 gm/L

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-298,1986

HS Code	2934999090

102-77-2

121-45-9

~67%

615-22-5

597-25-1

Literature: Brownbridge, P.; Jowett, I. C. Phosphorus and Sulfur and the Related Elements, 1988 , vol. 35, p. 311 - 318

96-36-6

102-77-2

~82%

597-25-1

149-30-4

Literature: Torii, Sigeru; Sayo, Noboru; Tanaka, Hideo Chemistry Letters, 1980 , p. 695 - 698

102-77-2

121-45-9

~89%

615-22-5

597-25-1

Detail

Literature: Torii, Sigeru; Sayo, Noboru; Tanaka, Hideo Chemistry Letters, 1980 , p. 695 - 698

110-91-8

813-77-4

597-25-1

Literature: Cheymol et al. Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1959 , vol. 249, p. 1240

67-56-1

7412-25-1

70531-19-0

597-25-1

Detail

Literature: Kasparek, Frantisek; Mollin, Jiri Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 2 p. 386 - 396

Precursor 7
102-77-2 121-45-9 96-36-6 110-91-8
813-77-4 67-56-1 7412-25-1
DownStream 0

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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