32434-44-9
32434-44-9 structure
- Name: Isofebrifugine
- Chemical Name: (+)-isofebrifugine
- CAS Number: 32434-44-9
- Molecular Formula: C16H19N3O3
- Molecular Weight: 301.34000
- Catalog: Research Areas Infection
- Create Date: 2016-06-05 09:41:19
- Modify Date: 2025-08-24 16:55:27
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Isofebrifugine, isolated from a Chinese medicinal plant, Chang Shan (Dichroa febrifuga), is a natural quinazolinone alkaloid with important physiological activities and good pharmacological effects. Antimalarial effect[1].
| Name | (+)-isofebrifugine |
|---|---|
| Synonyms |
(+)-inthomycin A
Phthoxazolin A 4,6,8-Decatrienamide,3-hydroxy-2,2,4-trimethyl-10-(5-oxazolyl)-,(R-(Z,Z,E)) Phthoxazolin (R-(Z,Z,E))-3-Hydroxy-2,2,4-trimethyl-10-(5-oxazolyl)-4,6,8-decatrienamide |
| Description | Isofebrifugine, isolated from a Chinese medicinal plant, Chang Shan (Dichroa febrifuga), is a natural quinazolinone alkaloid with important physiological activities and good pharmacological effects. Antimalarial effect[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.48±0.1 g/cm3 (20 ºC 760 Torr) |
|---|---|
| Boiling Point | 519.8±58.0 °C(Predicted) |
| Melting Point | 138-139 ºC |
| Molecular Formula | C16H19N3O3 |
| Molecular Weight | 301.34000 |
| Exact Mass | 301.14300 |
| PSA | 76.38000 |
| LogP | 0.95480 |
| Water Solubility | Very slightly soluble (0.28 g/L) (25 ºC) |
| Precursor 10 | |
|---|---|
| DownStream 1 | |
![benzyl (3aS,7aS)-2-hydroxy-2-[(4-oxo-3(4H)-quinazolinyl)methyl]hexahydrofuro[3,2-b]pyridine-4(2H)-carboxylate structure](https://image.chemsrc.com/caspic/096/304436-20-2.png)
![2,3-cis-3-benzyloxy-1-benzyloxycarbonyl-2-[2-oxo-3-(4-oxo-4H-quinazolin-3-yl)propyl]piperidin structure](https://image.chemsrc.com/caspic/202/391242-46-9.png)
![benzyl (3aS,7aS)-2-(bromomethyl)hexahydrofuro[3,2-b]pyridine-4(2H)-carboxylate structure](https://image.chemsrc.com/caspic/499/304436-18-8.png)
![(3AS,7AS)-BENZYL 2-(BROMOMETHYL)-2-METHOXYHEXAHYDROFURO[3,2-B]PYRIDINE-4(2H)-CARBOXYLATE structure](https://image.chemsrc.com/caspic/461/304436-19-9.png)
![(2S,3S)-2-[2-oxo-3-(4-oxo-4H-quinazolin-3-yl)propyl]-3-methoxymethoxypiperidine-1-carboxylic acid tert-butyl ester structure](https://image.chemsrc.com/caspic/354/1050609-27-2.png)
