174627-50-0
174627-50-0 structure
- Name: L-759633
- Chemical Name: 1-methoxy-6,6-dimethyl-9-methylidene-3-(2-methyloctan-2-yl)-7,8,10,10a-tetrahydro-6aH-benzo[c]chromene
- CAS Number: 174627-50-0
- Molecular Formula: C26H40O2
- Molecular Weight: 384.595
- Create Date: 2017-09-22 22:33:04
- Modify Date: 2025-08-25 23:59:09
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L-759,633 is high affinity, selective CB2 receptor agonist (Ki values are 6.4 and 1043 nM for CB2 and CB1 receptors respectively). L-759,633 potently inhibits forskolin-stimulated cAMP production via CB2 receptors expressed in CHO cells (EC50 = 8.1 nM).
| Name | 1-methoxy-6,6-dimethyl-9-methylidene-3-(2-methyloctan-2-yl)-7,8,10,10a-tetrahydro-6aH-benzo[c]chromene |
|---|---|
| Synonyms |
L-759,633
(6aR,10aR)-1-Methoxy-6,6,9-trimethyl-3-(2-methyl-2-octanyl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene 6H-Dibenzo[b,d]pyran, 3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-, (6aR,10aR)- |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 447.9±45.0 °C at 760 mmHg |
| Molecular Formula | C26H40O2 |
| Molecular Weight | 384.595 |
| Flash Point | 134.2±28.3 °C |
| Exact Mass | 384.302826 |
| PSA | 18.46000 |
| LogP | 9.70 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.500 |