103476-24-0

103476-24-0 structure

Name: D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt
Chemical Name: hexapotassium,(2,3,5-trihydroxy-4,6-diphosphonatooxycyclohexyl) phosphate
CAS Number: 103476-24-0
Molecular Formula: C₆H₉K₆O₁₅P₃
Molecular Weight: 648.638
Catalog: Research Areas Metabolic Disease
Create Date: 2018-12-11 12:57:54
Modify Date: 2024-01-04 18:01:12
D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is the hexapotassium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.

Name	hexapotassium,(2,3,5-trihydroxy-4,6-diphosphonatooxycyclohexyl) phosphate
Synonyms	1,2,3,4,5,6-Cyclohexanehexol, 1,2,4-tris(dihydrogen phosphate), potassium salt, (1R,2R,3S,4R,5R,6S)- (1:6) 1D-myo-inositol 1,3,4-triphosphate hexapotassium salt 2,4-bis[(dipotassiooxyphosphoryl)oxy]-3,5,6-trihydroxycyclohexyl dipotassium phosphate D-myo-INOSITOL-1,4,5-TRISPHOSPHATE (POTASSIUM SALT) Hexapotassium (1R,2R,3S,4R,5R,6S)-3,5,6-trihydroxy-1,2,4-cyclohexanetriyl tris(phosphate) MFCD00077799 Hexapotassium (1R,2R,3S,4R,5R,6S)-3,5,6-trihydroxycyclohexane-1,2,4-triyl tris(phosphate) D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt D-MYO-INOSITOL

Description	D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is the hexapotassium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Second messenger D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3) is served as an inositol phosphate derivative. The dissociation constant (KD) for Pr55Gag complexed with D-myo-Inositol 1,4,5-trisphosphate (an inositol with divalent phosphate groups and devoid of lipid groups) is 2170 μM. The binding affinities of D-myo-Inositol 1,4,5-trisphosphate (KD=568 μM) and 1,3,4,5-IP4 (KD=526 μM) for matrix (MA) are almost identical[1].
References	[1]. Anraku K, et al. Highly sensitive analysis of the interaction between HIV-1 Gag and phosphoinositide derivatives based on surface plasmon resonance. Biochemistry. 2010 Jun 29;49(25):5109-16.