25152-20-9

25152-20-9 structure

Name: Thymidine,5'-amino-5'-deoxy-
Chemical Name: 5'-amino-5'-deoxythymidine
CAS Number: 25152-20-9
Molecular Formula: C₁₀H₁₅N₃O₄
Molecular Weight: 241.24
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-12-06 15:17:42
Modify Date: 2025-08-22 18:18:39
5′-Amino-5′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5'-amino-5'-deoxythymidine
Synonyms	5'-Amino-5'-deoxy-D-thymidine 5'-amino-3'-hydroxythymidine 5'-amino-5'-deoxy-thymidine 5'-deoxy-5'-aminothymidine 5'-deoxy-5'-amino-deoxythymidine

Description	5′-Amino-5′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport

19316-85-9

~10%

25152-20-9

Literature: Wako Pure Chemical Industries, Ltd. Patent: US2008/64868 A1, 2008 ; Location in patent: Page/Page column 10; 11 ;

210490-66-7

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29391-35-3

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Literature: Challa, Hemavathi; Bruice, Thomas C. Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 6 p. 1475 - 1481

50-89-5

25152-20-9

Literature: Charles; Arya, Dev P. Journal of Carbohydrate Chemistry, 2005 , vol. 24, # 2 p. 145 - 160

7253-19-2

25152-20-9