5270-74-6

5270-74-6 structure

Name: Chlorthalidone impurity
Chemical Name: 2-(4-chloro-3-sulfamoylbenzoyl)benzoic acid
CAS Number: 5270-74-6
Molecular Formula: C₁₄H₁₀ClNO₅S
Molecular Weight: 339.75
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2017-12-15 21:13:40
Modify Date: 2025-08-25 14:37:54
Chlorthalidone impurity is a metabolite of Chlorthalidone (HY-15833). Chlorthalidone is a thiazide-like diuretic used to treat hypertension[1][2].

Name	2-(4-chloro-3-sulfamoylbenzoyl)benzoic acid
Synonyms	Chlorthalidone Related Compound A 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid 2-(4-Chloro-3-sulphamoylbenzoyl)benzoic acid EINECS 226-089-8

Description	Chlorthalidone impurity is a metabolite of Chlorthalidone (HY-15833). Chlorthalidone is a thiazide-like diuretic used to treat hypertension[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Bauer J, et al. Stability-indicating assay for chlorthalidone formulation: evaluation of the USP analysis and a high-performance liquid chromatographic analysis. J Pharm Sci. 1983 Aug;72(8):924-8. [2]. Barrios V, et al. Which thiazide to choose as add-on therapy for hypertension? Integr Blood Press Control. 2014 Jul 30;7:35-47.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P301 + P312 + P330-P305 + P351 + P338
RIDADR	NONH for all modes of transport
HS Code	2935009090

77-36-1

5270-74-6

Literature: Graf et al. Helvetica Chimica Acta, 1959 , vol. 42, p. 1085,1086

68592-12-1

5270-74-6

Literature: Graf et al. Helvetica Chimica Acta, 1959 , vol. 42, p. 1085,1086

118-04-7

5270-74-6

Literature: Graf et al. Helvetica Chimica Acta, 1959 , vol. 42, p. 1085,1086

Precursor 3
77-36-1 68592-12-1 118-04-7
DownStream 0

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%