1159977-58-8

1159977-58-8 structure

Name: 7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene
Chemical Name: 7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene
CAS Number: 1159977-58-8
Molecular Formula: C₄₂H₄₄N₂O₆S
Molecular Weight: 704.87400
Catalog: Research Areas Cancer
Create Date: 2017-02-07 12:03:09
Modify Date: 2025-08-26 20:45:01
7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene is a liver receptor homolog-1 (LRH-1) antagonist with an IC50 of 3.1 μM[1].

Name	7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene
Synonyms	[6-hydroxy-2-(4-hydroxyphenyl)-7-[4-(2-piperidin-1-ylethoxy)benzoyl]-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone

Description	7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene is a liver receptor homolog-1 (LRH-1) antagonist with an IC50 of 3.1 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene is binding to the domain (LBD) of LRH-1[1].
References	[1]. Rey, J., et al. Discovery of a New Class of Liver Receptor Homolog-1 (LRH-1) Antagonists: Virtual Screening, Synthesis and Biological Evaluation. ChemMedChem,2012; 7(11), 1909–1914.