| Name | aleo-emodin-8-O-β-D-glucopyranoside |
|---|---|
| Synonyms |
.aloe-emodin 8-O-β-glucoside
.aloe-emodin 8-O-glucoside ALOE-EMODIN-8-O-BETA-D-GLUCOPYRANOSIDE .8-O-β-D-glucopyranosyl-aloe-emodin 8-Hydroxy-6-(hydroxymethyl)-9,10-dioxo-9,10-dihydro-1-anthracenyl β-D-glucopyranoside .physcion-1-O-β-D-glucopyranoside .aloe-emodin-8-O-β-D-glucopyranoside 9,10-Anthracenedione, 8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)- aloe-emodin 8-O-β-D-glucopyranoside Aloeemodin-8-monoglucoside Aloe Emodin 8-Glucoside Aloe-emodin-8-O-β-D-glucoside |
| Description | Aloe-emodin-8-O-β-D-glucopyranoside, a compound isolated from Saussrurea lappa, is a moderate inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with an IC50 of 26.6 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50:26.6 μM (hPTP1B)[1] |
| References |
[1]. Li S, et al. PTP1B inhibitors from Saussrurea lappa. J Asian Nat Prod Res. 2006 Apr-May;8(3):281-6. |
| Density | 1.673±0.06 g/cm3 |
|---|---|
| Boiling Point | 829.9±65.0 °C at 760 mmHg |
| Melting Point | 236-237 ºC |
| Molecular Formula | C21H20O10 |
| Molecular Weight | 432.378 |
| Flash Point | 295.2±27.8 °C |
| Exact Mass | 432.105652 |
| PSA | 173.98000 |
| LogP | -0.10 |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
| Index of Refraction | 1.726 |
| Storage condition | 2-8℃ |
| Water Solubility | Insuluble (3.5E-3 g/L) (25 ºC) |