100490-21-9

100490-21-9 structure

Name: A7132
Chemical Name: 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid
CAS Number: 100490-21-9
Molecular Formula: C₁₉H₁₆F₂N₄O₃
Molecular Weight: 386.35200
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-12-18 14:36:23
Modify Date: 2024-01-15 05:46:28
A7132 is an antibacterial agent. A7132 possess broad and potent antibacterial activity.

Name	6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylic acid
Synonyms	1-p-fluorophenyl-6-fluoro-1,4-dihydro-4-oxo-7(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid sarafloxacin A7132

Description	A7132 is an antibacterial agent. A7132 possess broad and potent antibacterial activity.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection
Target	Antibacterial[1]
In Vitro	A7132 (Compound 31) shows great oral activity against S. aureus NCTC 10649, E. coli Juhl and P. aeruginosa 5007 with MICs of 0.25, 0.05 and 0.39 μg/mL, respectively[1].
References	[1]. Chu DT, et al. Synthesis and structure-activity relationships of new arylfluoronaphthyridine antibacterialagents. J Med Chem. 1986 Nov;29(11):2363-9.