100477-88-1

100477-88-1 structure

Name: Entadamide A
Chemical Name: (E)-N-(2-hydroxyethyl)-3-methylsulfanylprop-2-enamide
CAS Number: 100477-88-1
Molecular Formula: C₆H₁₁NO₂S
Molecular Weight: 161.22
Catalog: Research Areas Infection
Create Date: 2017-09-21 20:52:37
Modify Date: 2025-08-27 10:12:00
Entadamide A (compound 1) is a tryptophan derivative. Entadamide A prevents tryptophan depletion by inhibiting indoleamine 2, 3-dioxygenase (IDO), thereby inhibiting HIV replication. Entadamide A can be used in drug and neuropsychiatric studies of redesivir [1].

Name	(E)-N-(2-hydroxyethyl)-3-methylsulfanylprop-2-enamide
Synonyms	entadamide A 2-Propenamide,n-(2-hydroxyethyl)-3-(methylthio)-,(E) N-(2-Hydroxyethyl)-3-methylthiopropenamide

Description	Entadamide A (compound 1) is a tryptophan derivative. Entadamide A prevents tryptophan depletion by inhibiting indoleamine 2, 3-dioxygenase (IDO), thereby inhibiting HIV replication. Entadamide A can be used in drug and neuropsychiatric studies of redesivir [1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Nzowa LK, et al. Two new tryptophan derivatives from the seed kernels of Entada rheedei: effects on cell viability and HIV infectivity. Fitoterapia. 2013 Jun;87:37-42.