76079-06-6

76079-06-6 structure

Name: FA-Ala-Arg-OH
Chemical Name: (2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]propanoyl]amino]pentanoic acid
CAS Number: 76079-06-6
Molecular Formula: C₁₆H₂₃N₅O₅
Molecular Weight: 365.38
Catalog: Biochemical Amino acids and their derivatives Arginine derivatives
Create Date: 2018-06-07 17:36:30
Modify Date: 2024-01-03 12:37:06
FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells[1].

Name	(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]propanoyl]amino]pentanoic acid
Synonyms	L-Arginine,N(2)-(N-(3-(2-furanyl)-1-oxo-2-propenyl)-L-alanyl) FA-Ala-arg Furylacryloylalanylarginine (2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(E)-3-furan-2-ylprop-2-enoyl]amino]propanoyl]amino]pentanoic acid Furylacryloyl-ala-arg

Description	FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells[1].
Related Catalog	Research Areas >> Endocrinology
References	[1]. Abdelmagid SA, et al. Prolactin and estrogen up-regulate carboxypeptidase-d to promote nitric oxide production and survival of mcf-7 breast cancer cells. Endocrinology. 2008 Oct;149(10):4821-8.