68573-24-0

68573-24-0 structure

Name: N-(p-Coumaroyl) Serotonin
Chemical Name: N-(p-Coumaroyl) Serotonin
CAS Number: 68573-24-0
Molecular Formula: C₁₉H₁₈N₂O₃
Molecular Weight: 322.35800
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK PDGFR
Create Date: 2017-08-12 20:15:49
Modify Date: 2025-08-25 12:44:45
N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower and has antioxidative, anti-atherogenic and anti-inflammatory properties. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca2+ release from sarcoplasmic reticulum[1]. N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research[2].

Name	N-(p-Coumaroyl) Serotonin
Synonyms	ipobscurine A

Description	N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower and has antioxidative, anti-atherogenic and anti-inflammatory properties. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca2+ release from sarcoplasmic reticulum[1]. N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research[2].
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
References	[1]. Tetsuya Takimoto, et al. Effect of N-(p-coumaroyl)serotonin and N-feruloylserotonin, major anti-atherogenic polyphenols in safflower seed, on vasodilation, proliferation and migration of vascular smooth muscle cells. Mol Nutr Food Res. 2011 Oct;55(10):1561-71. [2]. Shin-ichiro Katsuda, et al. Safflower seed polyphenols (N-(p-coumaroyl)serotonin and N-feruloylserotonin) ameliorate atherosclerosis and distensibility of the aortic wall in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits.Hypertens Res

Hazard Codes	Xi

7400-08-0

153-98-0

~70%

68573-24-0

Literature: Ajinomoto Co., Inc. Patent: EP1935419 A1, 2008 ; Location in patent: Page/Page column 10 ;

50-67-9

7400-08-0

~80%

68573-24-0

Literature: Somei, Masanori; Morikawa, Harunobu; Yamada, Koji; Yamada, Fumio Heterocycles, 1998 , vol. 48, # 6 p. 1117 - 1120

61-54-1

68573-24-0

Literature: Somei, Masanori; Morikawa, Harunobu; Yamada, Koji; Yamada, Fumio Heterocycles, 1998 , vol. 48, # 6 p. 1117 - 1120

212707-60-3

68573-24-0

Literature: Somei, Masanori; Morikawa, Harunobu; Yamada, Koji; Yamada, Fumio Heterocycles, 1998 , vol. 48, # 6 p. 1117 - 1120

212707-63-6

68573-24-0

Literature: Somei, Masanori; Morikawa, Harunobu; Yamada, Koji; Yamada, Fumio Heterocycles, 1998 , vol. 48, # 6 p. 1117 - 1120

212707-68-1

~5%

68573-24-0

Literature: Somei, Masanori; Morikawa, Harunobu; Yamada, Koji; Yamada, Fumio Heterocycles, 1998 , vol. 48, # 6 p. 1117 - 1120

Precursor 4
7400-08-0 153-98-0 50-67-9 61-54-1
DownStream 0