216064-36-7

216064-36-7 structure
216064-36-7 structure

Name β-Pompilidotoxin
Synonyms RIKIGLFDQLSRL-NH2
Beta-Pompilidotoxin
b-Pompilidotoxin
Description β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells[1].
Related Catalog
In Vitro β-Pompilidotoxin (β-PMTX) increases resurgent current in wild-type neurons and induced resurgent current in med neurons. β-Pompilidotoxin (10 μM) modestly but significantly increased the decay time constant (τdecay) of currents evoked by a step from -90 to 0 mV from 0.52 to 0.73 msec in wild-type Purkinje cells[1].
References

[1]. Tina M Grieco, et al. Production of resurgent current in NaV1.6-null Purkinje neurons by slowing sodium channel inactivation with beta-pompilidotoxin. J Neurosci. 2004 Jan 7;24(1):35-42.

Molecular Formula C71H124N22O17
Molecular Weight 1557.88000
Exact Mass 1556.95000
PSA 668.75000
LogP 4.98310
WGK Germany 3