43077-30-1
43077-30-1 structure
- Name: DPO-1
- Chemical Name: [[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene
- CAS Number: 43077-30-1
- Molecular Formula: C22H29OP
- Molecular Weight: 340.43900
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
- Create Date: 2017-03-12 13:51:48
- Modify Date: 2025-08-27 20:53:41
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DPO-1 is a potent inhibitor of the voltage-gated potassium channel subtype Kv1.5 and a blocker of ultrarapid delayed rectifier potassium current. DPO-1 prevents atrial arrhythmia[1][2].
| Name | [[(1S,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl]-phenylphosphoryl]benzene |
|---|---|
| Synonyms |
DPO-1
HMS3269O11 neomenthyldiphenylphosphine oxide Neomenthyldiphenylphosphin-oxid HMS3261N07 |
| Description | DPO-1 is a potent inhibitor of the voltage-gated potassium channel subtype Kv1.5 and a blocker of ultrarapid delayed rectifier potassium current. DPO-1 prevents atrial arrhythmia[1][2]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.054g/cm3 |
|---|---|
| Boiling Point | 434.966ºC at 760 mmHg |
| Molecular Formula | C22H29OP |
| Molecular Weight | 340.43900 |
| Flash Point | 216.86ºC |
| Exact Mass | 340.19600 |
| PSA | 26.88000 |
| LogP | 5.46130 |
| Index of Refraction | 1.547 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2902909090 |
|
~56%
43077-30-1 |
| Literature: Yamashita, Mitsuji; Soeda, Yukio; Suzuki, Nobuyoshi; Yamada, Manabu; Tsunekawa, Kenji; et al. Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 6 p. 1871 - 1872 Title/Abstract Full Text Show Details Yamashita, Mitsuji; Suzuki, Nobuyoshi; Yamada, Manabu; Soeda, Yukio; Yamashita, Hiroaki; et al. Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 1 p. 219 - 222 |
|
~%
43077-30-1 |
| Literature: Beaumont; Kiely; Rooney Journal of Fluorine Chemistry, 2001 , vol. 108, # 1 p. 47 - 50 |
|
~%
43077-30-1 |
| Literature: Yamashita, Mitsuji; Suzuki, Nobuyoshi; Yamada, Manabu; Soeda, Yukio; Yamashita, Hiroaki; et al. Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 1 p. 219 - 222 |
| Precursor 4 | |
|---|---|
| DownStream 0 | |
| HS Code | 2902909090 |
|---|---|
| Summary | 2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0% |