193744-04-6

193744-04-6 structure

Name: N-[[(3R)-1-(AMINOIMINOMETHYL)-3-PIPERIDINYL]ACETYL]-4-(PHENYLETHYNYL)-L-PHENYLALANINE METHYL ESTER TRIFLUOROACETATE
Chemical Name: methyl (2S)-2-[[2-[(3R)-1-carbamimidoylpiperidin-3-yl]acetyl]amino]-3-[4-(2-phenylethynyl)phenyl]propanoate,2,2,2-trifluoroacetic acid
CAS Number: 193744-04-6
Molecular Formula: C₂₆H₃₀N₄O₃
Molecular Weight: 446.54
Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
Create Date: 2016-06-08 09:21:34
Modify Date: 2025-08-20 20:33:03
Ro26-4550 is a low micromolar antagonist of IL-2/IL-2Rα binding with an IC50 value of 3 μM[1].

Name	methyl (2S)-2-[[2-[(3R)-1-carbamimidoylpiperidin-3-yl]acetyl]amino]-3-[4-(2-phenylethynyl)phenyl]propanoate,2,2,2-trifluoroacetic acid
Synonyms	Ro26-4550 Ro 26-4550 trifluoroacetate IL-2Ralpha Antagonist

Description	Ro26-4550 is a low micromolar antagonist of IL-2/IL-2Rα binding with an IC50 value of 3 μM[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology
References	[1]. Braisted AC, et al. Discovery of a potent small molecule IL-2 inhibitor through fragment assembly. J Am Chem Soc. 2003 Apr 2;125(13):3714-5.