527-75-3

527-75-3 structure

527-75-3 structure

Name: berythromycin
Chemical Name: erythromycin B
CAS Number: 527-75-3
Molecular Formula: C₃₇H₆₇NO₁₂
Molecular Weight: 717.927
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2018-07-19 12:08:46
Modify Date: 2024-01-02 20:12:09

Name	erythromycin B
Synonyms	12-Deoxyerythromycin (3R,4S,5S,6R,7R,9R,11R,12S,13R,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione berythromycinum berythromycin beritromicina berythromycine (3R,4S,6R,7R,9R,11R,12S,13R,14R)-6-[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12-dihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione erythromycin B (3R,4S,5S,6R,7R,9R,11R,12S,13R,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12-dihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione (non-preferred name) berythromycinum [INN_la] Erythromycin Impurity 2

Density	1.2±0.1 g/cm3
Boiling Point	807.6±65.0 °C at 760 mmHg
Melting Point	168-170ºC (dec)
Molecular Formula	C₃₇H₆₇NO₁₂
Molecular Weight	717.927
Flash Point	442.2±34.3 °C
Exact Mass	717.466309
PSA	173.68000
LogP	3.12
Vapour Pressure	0.0±6.5 mmHg at 25°C
Index of Refraction	1.527
Storage condition	20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KF4700000

CHEMICAL NAME :: Erythromycin, 12-deoxy-

CAS REGISTRY NUMBER :: 527-75-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C37-H67-N-O12

MOLECULAR WEIGHT :: 718.05

WISWESSER LINE NOTATION :: T-14-VO GVTJ C2 D1 EQ F1 H1 JQ J1 L1 N1 KO- BT6OTJ CQ DN1&1 F1& MO- FT6OTJ B1 CQ DO1 D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 2,58,1980

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Hazard Codes	Xi
Risk Phrases	36
Safety Phrases	26
RIDADR	NONH for all modes of transport

Precursor 2
188786-14-3 188786-05-2
DownStream 0