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2807-30-9

2807-30-9 structure
2807-30-9 structure
Name 2-propoxyethanol
Synonyms 2-Propoxyethanol
2-hydroxyethyl propyl ether
propylcellosolve
Ethylene Glycol Monopropyl Ether
2-n-propoxyethanol
Propyl Cellosolve
3-oxa-1-hexanol
MFCD00072645
Extrasolve EP
Eastman EP
Propoxyethanol
N-PROPYL GLYCOL
ektasolveep
EINECS 220-548-6
n-Propylglykol
2-propoxy-1-ethanol
PROPYL GLYCOL
ep solvent
Density 0.913 g/mL at 25 °C(lit.)
Boiling Point 150-153 °C(lit.)
Melting Point −75 °C(lit.)
Molecular Formula C5H12O2
Molecular Weight 104.14800
Flash Point 120 °F
Exact Mass 104.08400
PSA 29.46000
LogP 0.40530
Vapour Pressure 0.00205mmHg at 25°C
Index of Refraction n20/D 1.413(lit.)
Storage condition Flammables area
Stability Flammable. Incompatible with oxidizing agents. May form explosive mixtures with air.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KM2800000
CHEMICAL NAME :
Ethanol, 2-propoxy-
CAS REGISTRY NUMBER :
2807-30-9
BEILSTEIN REFERENCE NO. :
1731983
LAST UPDATED :
199710
DATA ITEMS CITED :
20
MOLECULAR FORMULA :
C5-H12-O2
MOLECULAR WEIGHT :
104.17
WISWESSER LINE NOTATION :
Q2O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,628,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,165,1984
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,628,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,165,1984 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3089 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,165,1984
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2000 ppm/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,343,1949
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1774 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570960
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1530 ppm/7H
TOXIC EFFECTS :
Behavioral - analgesia Lungs, Thorax, or Respiration - dyspnea Kidney, Ureter, Bladder - hematuria
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 25,157,1943
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
960 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Behavioral - tremor Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,165,1984 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
11700 mg/kg/6W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - hematuria Endocrine - changes in spleen weight Blood - changes in erythrocyte (RBC) count
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,165,1984
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 ppm/6H/2W-I
TOXIC EFFECTS :
Endocrine - changes in spleen weight Blood - changes in other cell count (unspecified) Blood - changes in erythrocyte (RBC) count
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 57,165,1984 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
100 ppm/6H
SEX/DURATION :
female 6-15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 32,93,1985
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
16 gm/kg
SEX/DURATION :
female 7-14 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - stillbirth
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB86-197605 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-THE NETHERLANDS:TWA 10 ppm (44 mg/m3);Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3118 No. of Facilities: 11635 (estimated) No. of Industries: 73 No. of Occupations: 26 No. of Employees: 73812 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3118 No. of Facilities: 10270 (estimated) No. of Industries: 80 No. of Occupations: 68 No. of Employees: 99040 (estimated) No. of Female Employees: 17756 (estimated)
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning
Hazard Statements H226-H312-H319
Precautionary Statements P280-P305 + P351 + P338
Hazard Codes Xn: Harmful;
Risk Phrases R21
Safety Phrases S26-S36/37-S46
RIDADR UN 1986 3/PG 3
WGK Germany 1
RTECS KM2800000
Packaging Group III
Hazard Class 3.2
2568-96-9 structure

2568-96-9

~%

2807-30-9 structure

2807-30-9

18854-56-3 structure

18854-56-3

Literature: EASTMAN CHEMICAL COMPANY Patent: US2012/330069 A1, 2012 ; Location in patent: Page/Page column 8 ;
75-21-8 structure

75-21-8

71-23-8 structure

71-23-8

~%

2807-30-9 structure

2807-30-9

Literature: Ashburn; Collett; Lazzell Journal of the American Chemical Society, 1935 , vol. 57, p. 1862
75-21-8 structure

75-21-8

6819-41-6 structure

6819-41-6

~%

2807-30-9 structure

2807-30-9

Literature: Cretcher; Pittenger Journal of the American Chemical Society, 1924 , vol. 46, p. 1503
6819-41-6 structure

6819-41-6

107-07-3 structure

107-07-3

~%

2807-30-9 structure

2807-30-9

Literature: Cretcher; Pittenger Journal of the American Chemical Society, 1924 , vol. 46, p. 1503
107-21-1 structure

107-21-1

~%

2807-30-9 structure

2807-30-9

Literature: Riemschneider; Schneider Monatshefte fuer Chemie, 1959 , vol. 90, p. 510,516
106-94-5 structure

106-94-5

107-21-1 structure

107-21-1

~%

2807-30-9 structure

2807-30-9

Literature: Wormuth, Klaus R.; Kaler, Eric W. Journal of Physical Chemistry, 1989 , vol. 93, # 12 p. 4855 - 4861
107-08-4 structure

107-08-4

107-21-1 structure

107-21-1

~%

2807-30-9 structure

2807-30-9

Literature: Palomaa Chemische Berichte, 1902 , vol. 35, p. 3300 Chemische Berichte, 1909 , vol. 42, p. 3874
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