Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: α-Cyclohexylmandelic acid
Price: ￥368.0/25g ￥148.0/5g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Alpha-Cyclohexylmandelic Acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 2-Cyclohexylmandelic acid
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

4335-77-7

4335-77-7 structure

4335-77-7 structure

Name: α-Cyclohexylmandelic acid
Chemical Name: 2-Cyclohexylmandelic acid
CAS Number: 4335-77-7
Molecular Formula: C₁₄H₁₈O₃
Molecular Weight: 234.291
Create Date: 2018-03-17 08:00:00
Modify Date: 2024-01-02 18:26:28

Name	2-Cyclohexylmandelic acid
Synonyms	UNII:QH762W903U α-Cyclohexylmandelic acid alpha-Cyclohexylmandelic acid α-Cyclohexyl-DL-mandelic Acid 2-Cyclohexyl-2-phenylglycolic acid Cyclohexylphenylglycolic acid MFCD00194543 2-Cyclohexyl-2-hydroxy-2-phenylacetic acid EINECS 224-380-4 Cyclohexyl(hydroxy)phenylacetic acid Benzeneacetic acid, α-cyclohexyl-α-hydroxy-

Density	1.2±0.1 g/cm3
Boiling Point	408.6±25.0 °C at 760 mmHg
Melting Point	163 °C
Molecular Formula	C₁₄H₁₈O₃
Molecular Weight	234.291
Flash Point	215.1±19.7 °C
Exact Mass	234.125595
PSA	57.53000
LogP	3.33
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.574
Storage condition	-20°C Freezer

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GV2770000

CHEMICAL NAME :: Cyclohexaneglycolic acid, alpha-phenyl-

CAS REGISTRY NUMBER :: 4335-77-7

LAST UPDATED :: 199206

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2668 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 19,5182,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 708 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 19,5182,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1270 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 19,5182,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 524 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 19,5182,1985

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 420 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 116,154,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 245 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - excitement Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 19,5182,1985

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H315-H318-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn,N,F
Risk Phrases	R22:Harmful if swallowed. R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . R67:Vapors may cause drowsiness and dizziness. R65:Harmful: May cause lung damage if swallowed. R38:Irritating to the skin. R
Safety Phrases	S60-S61-S62
RIDADR	UN3082 9/PG 3
RTECS	TF1410000
HS Code	2918199090

Precursor 10
31197-69-0 10399-13-0 424792-60-9 424792-59-6
76-93-7 1603-79-8 931-50-0 4358-87-6
1508-65-2 108-85-0
DownStream 8
5633-20-5 712-50-5 10399-13-0 52034-92-1
50-10-2 7146-19-2 6313-70-8 3894-09-5

HS Code	2918199090
Summary	2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%