868390-90-3
868390-90-3 structure
- Name: pyrimorph
- Chemical Name: pyrimorph
- CAS Number: 868390-90-3
- Molecular Formula: C22H25ClN2O2
- Molecular Weight: 384.90
- Catalog: Signaling Pathways Anti-infection Fungal
- Create Date: 2017-09-14 17:46:55
- Modify Date: 2024-01-04 19:58:20
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Pyrimorph is a fungicide with excellent antifungal activity against oomycetes[1].
| Name | pyrimorph |
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| Description | Pyrimorph is a fungicide with excellent antifungal activity against oomycetes[1]. |
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| Related Catalog | |
| In Vitro | Pyrimorph inhibits different stages in the life cycle of P.capsici: mycelial growth (EC50 = 1.84 μg/mL), sporangia formation (EC50 = 0.17 μg/mL), zoospore release (EC50 = 4.92 μg/mL), cystospore germination (EC50 = 0.09 μg/mL)[1]. Pyrimorph exhibits 40.95% inhibition of oxygen consumption of intact mycelia at 100 μg/mL[1]. Pyrimorph inhibits the synthesis of cell wall either directly or indirectly from ultrastructural transformation of cell wall thickening and disruption of vacuoles[1]. |
| In Vivo | Pyrimorph (0-28 mg/L; exposure; 0-192 h) has low toxicity and accumulates quickly in zebrafish[2]. Animal Model: Zebrafish (Brachydanio rerio), with an average body weight and length of about 0.30±0.10 g and 3.00±0.50 cm, respectively[2] Dosage: 0-28 mg/L Administration: Exposure, 0-192 h Result: Had low toxicity to zebrafish, with LC50 values ranging from 24.33 mg/L (24 h) to 19.79 mg/L (96 h). Accumulated in fish shortly. |
| References |
| Melting Point | 131-133 °C |
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| Molecular Formula | C22H25ClN2O2 |
| Molecular Weight | 384.90 |
| Exact Mass | 384.16000 |
| PSA | 42.43000 |
| LogP | 4.26090 |
| Storage condition | -20°C |
| Hazard Codes | Xn |
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