471-05-6

471-05-6 structure

Name: zerumbone
Chemical Name: zerumbone
CAS Number: 471-05-6
Molecular Formula: C₁₅H₂₂O
Molecular Weight: 218.335
Catalog: Signaling Pathways Anti-infection HSV
Create Date: 2018-03-06 08:00:00
Modify Date: 2025-08-21 16:34:36
Zerumbone is a monocyclic sesquiterpene compound isolated from the rhizomes of Zingiber zerumbet Smith. Zerumbone potently inhibits the activation of Epstein-Barr virus with an IC50 of 0.14 mM. Zerumbone has anti-cancer, antioxidant, anti-inflammatory and anti-proliferative activity[1][2].

Name	zerumbone
Synonyms	(2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one (2E,6E,10E)-2,6,9,9-Tetramethylcycloundeca-2,6,10-trien-1-one 2,6,10-Cycloundecatrien-1-one, 2,6,9,9-tetramethyl-, (2E,6E,10E)- ZERUMBONE ((2E,6E,10E)-2,6,9,9-TETRAMETHYLCYCLOUNDECA-2,6,10-TRIEN-1-ONE) zerumbone

Description	Zerumbone is a monocyclic sesquiterpene compound isolated from the rhizomes of Zingiber zerumbet Smith. Zerumbone potently inhibits the activation of Epstein-Barr virus with an IC50 of 0.14 mM. Zerumbone has anti-cancer, antioxidant, anti-inflammatory and anti-proliferative activity[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> HSV Research Areas >> Infection
References	[1]. Murakami A, et al. Identification of zerumbone in Zingiber zerumbet Smith as a potent inhibitor of 12-O-tetradecanoylphorbol-13-acetate-induced Epstein-Barr virus activation. Biosci Biotechnol Biochem. 1999 Oct;63(10):1811-2. [2]. Kalantari K, et al. A Review of the Biomedical Applications of Zerumbone and the Techniques for Its Extractionfrom Ginger Rhizomes. Molecules. 2017 Sep 30;22(10).