BioBioPha
China
Product Name: Kushenol X
Price: ￥4150.0/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Kushenol X
Price: ￥5600.0/5mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Kushenol X
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

254886-77-6

254886-77-6 structure

254886-77-6 structure

Name: Kushenol X
Chemical Name: Kushenol X
CAS Number: 254886-77-6
Molecular Formula: C₂₅H₂₈O₇
Molecular Weight: 440.486
Catalog: Natural product Flavonoids
Create Date: 2016-11-07 04:24:06
Modify Date: 2024-01-02 11:33:54
Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC50s of 2.07 μM and 3.05 μM, respectively[1][2].

Name	Kushenol X
Synonyms	4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-8-[5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2R,3R)- (2R,3R)-2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-8-[(2R)-2-isopropenyl-5-methyl-4-hexen-1-yl]-2,3-dihydro-4H-chromen-4-one Kushenol X (2R,3R)-2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-8-(2-isopropenyl-5-methyl-4-hexen-1-yl)-2,3-dihydro-4H-chromen-4-one 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-, (2R,3R)-

Description	Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC50s of 2.07 μM and 3.05 μM, respectively[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	IC50: 2.07 μM (β-glucuronidase)[1] and 3.05 μM (Human carboxylesterase 2 (hCE2))[2]
References	[1]. Cheng-Peng Sun, et al. The study of inhibitory effect of natural flavonoids toward β-glucuronidase and interaction of flavonoids with β-glucuronidase. Int J Biol Macromol. 2020 Jan 15;143:349-358. [2]. Sha-Sha Song, et al. Flavonoids as human carboxylesterase 2 inhibitors: Inhibition potentials and molecular docking simulations. Int J Biol Macromol. 2019 Jun 15;131:201-208.

Density	1.3±0.1 g/cm3
Boiling Point	699.6±55.0 °C at 760 mmHg
Molecular Formula	C₂₅H₂₈O₇
Molecular Weight	440.486
Flash Point	238.8±25.0 °C
Exact Mass	440.183502
PSA	127.45000
LogP	5.74
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.640

Hazard Codes	Xi