257612-36-5

257612-36-5 structure

Name: Synstab A
Chemical Name: 4-bromo-N-[2,2,2-trichloro-1-(4-sulfamoylanilino)ethyl]benzamide
CAS Number: 257612-36-5
Molecular Formula: C₁₅H₁₃BrCl₃N₃O₃S
Molecular Weight: 501.61
Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
Create Date: 2017-06-03 17:37:49
Modify Date: 2025-09-12 10:26:51
Synstab A is a mitosis modulator to promote interactions between α- and β-tubulin. Synstab A can polymerizes microtubules from purified tubulin, and produces microtubule bundles in interphase cells[1][2].

Name	4-bromo-N-[2,2,2-trichloro-1-(4-sulfamoylanilino)ethyl]benzamide

Description	Synstab A is a mitosis modulator to promote interactions between α- and β-tubulin. Synstab A can polymerizes microtubules from purified tubulin, and produces microtubule bundles in interphase cells[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
Target	α-Tubulin and β-Tubulin interaction[1]
References	[1]. Gerry CJ, et al. Unifying principles of bifunctional, proximity-inducing small molecules. Nat Chem Biol. 2020 Apr;16(4):369-378. [2]. Beyer CF, et al. TTI-237: a novel microtubule-active compound with in vivo antitumor activity. Cancer Res. 2008 Apr 1;68(7):2292-300.