Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Febrifugine dihydrochloride
Price: Check
Purity: 99.85%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: (+)-Febrifugine dihydrochloride
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: rac-Febrifugine Dihydrochloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

32434-42-7

32434-42-7 structure

32434-42-7 structure

Name: Febrifugine dihydrochloride
Chemical Name: 3-[3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one,dihydrochloride
CAS Number: 32434-42-7
Molecular Formula: C₁₆H₂₁Cl₂N₃O₃
Molecular Weight: 374.26200
Catalog: Research Areas Infection
Create Date: 2016-12-06 23:02:26
Modify Date: 2024-01-05 15:24:15
Febrifugine dihydrochloride is a quinazolinone alkaloid found in the roots and leaves of Dichroa febrifuga, with antimalarial activity[1].

Name	3-[3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one,dihydrochloride
Synonyms	Febrifugine dihydrochloride [MI] 2-Propanol,1-((6-hydrazinyl-3-pyridazinyl)methylamino)-,hydrochloride (1:2) UNII-K922TFG9SM Pildralazine dihydrochloride [MI] 1-((6-Hydrazinyl-3-pyridazinyl)methylamino)-2-propanol 3-(3-((2R,3S)-3-Hydroxy-2-piperidinyl)-2-oxopropyl)-4(3H)-quinazolinone dihydrochloride Febrifugine dihydrochloride

Description	Febrifugine dihydrochloride is a quinazolinone alkaloid found in the roots and leaves of Dichroa febrifuga, with antimalarial activity[1].
Related Catalog	Research Areas >> Infection
References	[1]. Herman JD, et al. The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs. Sci Transl Med. 2015 May 20;7(288):288ra77. [2]. Herman JD, et al. The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs. Sci Transl Med. 2015 May 20;7(288):288ra77.

Melting Point	220-222 °C (decomp)
Molecular Formula	C₁₆H₂₁Cl₂N₃O₃
Molecular Weight	374.26200
Exact Mass	373.09600
PSA	84.22000
LogP	2.40140
Appearance	powder，off-white to gray to brown

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Hazard Codes	Xn
RIDADR	NONH for all modes of transport

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