52436-88-1

52436-88-1 structure

Name: β-Nor-lapachone
Chemical Name: 2,2-dimethyl-3H-benzo[g][1]benzofuran-4,5-dione
CAS Number: 52436-88-1
Molecular Formula: C₁₄H₁₂O₃
Molecular Weight: 228.24
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2016-08-24 05:58:32
Modify Date: 2025-08-25 07:30:36
β-Nor-lapachone is a Candida glabrata antibiofilm agent. β-Nor-lapachone can stimulate ROS production, inhibits efflux activity, adhesion, biofilm formation and the metabolism of mature biofilms of Candida glabrata. β-Nor-lapachone has antifungal activity[1].

Name	2,2-dimethyl-3H-benzo[g][1]benzofuran-4,5-dione
Synonyms	Naphtho[1,2-b]furan-4,5-dione,2,3-dihydro-2,2-dimethyl

Description	β-Nor-lapachone is a Candida glabrata antibiofilm agent. β-Nor-lapachone can stimulate ROS production, inhibits efflux activity, adhesion, biofilm formation and the metabolism of mature biofilms of Candida glabrata. β-Nor-lapachone has antifungal activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS
Target	Candida glabrata, ROS[1]
References	[1]. Clemente de Moraes D, et al. Effects of β-lapachone and β-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata. Bioorg Med Chem. 2022;63:116749.