1121-30-8

1121-30-8 structure

1121-30-8 structure

Name: Pyrithione
Chemical Name: pyrithione
CAS Number: 1121-30-8
Molecular Formula: C₅H₅NOS
Molecular Weight: 127.16400
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-09-27 18:55:43
Modify Date: 2024-01-06 12:32:36
Pyrithione is a compound with antibacterial and antifungal activity[1].

Name	pyrithione
Synonyms	1-hydroxy-2-pyridinethione 2-PYRIDINETHIONE,1-HYDROXY N-HYDROXYPYRIDINE-2-THIONE PTO 1-hydroxypyridine-2-thione N-hydroxy-2-pyridinethione EINECS 214-328-9 1-hydroxyl-1H-pyridine-2-thione SQ-2113

Description	Pyrithione is a compound with antibacterial and antifungal activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. PANSY FE, et al. In vitro studies with 1-hydroxy-2(1H) pyridinethione. Proc Soc Exp Biol Med. 1953 Jan;82(1):122-4.

Density	1.43g/cm3
Boiling Point	253.8ºC at 760mmHg
Molecular Formula	C₅H₅NOS
Molecular Weight	127.16400
Flash Point	107.3ºC
Exact Mass	127.00900
PSA	57.25000
LogP	1.45490
Vapour Pressure	0.00275mmHg at 25°C
Index of Refraction	1.732
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UT9625000

CHEMICAL NAME :: 2-(1H)-Pyridinethione, 1-hydroxy-

CAS REGISTRY NUMBER :: 1121-30-8

BEILSTEIN REFERENCE NO. :: 0109936

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C5-H5-N-O-S

MOLECULAR WEIGHT :: 127.17

WISWESSER LINE NOTATION :: T6NYJ AQ BUS

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 535 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,156,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 165 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,156,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,156,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 340 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 2,156,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 108 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOANDB Toxicology Annual. (New York, NY) 1974/75-79. Discontinued. Volume(issue)/page/year: 3,1,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - wild bird species

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

HS Code	2933399090

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%