80557-12-6

80557-12-6 structure

Name: Grifolic acid
Chemical Name: 2,4-Dihydroxy-6-methyl-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecat rien-1-yl]benzoic acid
CAS Number: 80557-12-6
Molecular Formula: C₂₃H₃₂O₄
Molecular Weight: 372.498
Catalog: Natural product Phenols
Create Date: 2017-04-26 15:19:40
Modify Date: 2025-08-24 18:50:15
Grifolic acid is a phenolic compound that is first extracted from the mushroom Albatrellus confluens. Grifolic acid acts as an agonist of the free fatty acid receptor (FFAR4/GPR120)[1].

Name	2,4-Dihydroxy-6-methyl-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecat rien-1-yl]benzoic acid
Synonyms	2,4-Dihydroxy-6-methyl-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]benzoic acid Benzoic acid, 2,4-dihydroxy-6-methyl-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]- Grifolic acid

Description	Grifolic acid is a phenolic compound that is first extracted from the mushroom Albatrellus confluens. Grifolic acid acts as an agonist of the free fatty acid receptor (FFAR4/GPR120)[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GPR120 Research Areas >> Inflammation/Immunology
In Vitro	Grifolic acid (2.5-20 µM) treatment reduces RAW264.7 cell viability in a dose and time dependent manner[1].
References	[1]. Zhao Y, et al. Grifolic acid induces mitochondrial membrane potential loss and cell death of RAW264.7 macrophages. Mol Med Rep. 2018;17(2):3281-3287.

Hazard Codes	Xi