509-80-8

509-80-8 structure

Name: Mitraphylline
Chemical Name: methyl (1S,4aS,5aS,6R,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
CAS Number: 509-80-8
Molecular Formula: C₂₁H₂₄N₂O₄
Molecular Weight: 368.42600
Catalog: Chemical pesticide Insecticide Organophosphorus pesticide
Create Date: 2017-08-23 11:25:40
Modify Date: 2025-08-25 09:40:53
Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils[1].

Name	methyl (1S,4aS,5aS,6R,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
Synonyms	ajmalicine oxindole-B HMS2267P09 Mitraphilline EINECS 208-106-0 rubradinine Mitraphylline Mitraphyllin

Description	Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Montserrat-de la Paz S, et al. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils. Phytomedicine. 2016 Feb 15;23(2):141-8.