946150-57-8

946150-57-8 structure

Name: Remetinostat
Chemical Name: methyl 4-[8-(hydroxyamino)-8-oxooctanoyl]oxybenzoate
CAS Number: 946150-57-8
Molecular Formula: C₁₆H₂₁NO₆
Molecular Weight: 323.34100
Catalog: Signaling Pathways Cell Cycle/DNA Damage HDAC
Create Date: 2017-05-05 20:48:18
Modify Date: 2024-01-02 18:28:28
Remetinostat (SHP-141) is a hydroxamic acid-based inhibitor of histone deacetylase enzymes (HDAC) which is under development for the treatment of cutaneous T-cell lymphoma[1].

Name	methyl 4-[8-(hydroxyamino)-8-oxooctanoyl]oxybenzoate
Synonyms	Benzoic acid,8-dioxooctyl]oxy]-,methyl ester (MP-shape) Methylparaben suberohydroxamic acid phenyl ester Remetinostat

Description	Remetinostat (SHP-141) is a hydroxamic acid-based inhibitor of histone deacetylase enzymes (HDAC) which is under development for the treatment of cutaneous T-cell lymphoma[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Epigenetics >> HDAC Research Areas >> Cancer
Target	HDAC[1].
References	[1]. Yijun Deng, et al. Process Development of the Soft Histone Deacetylate Enzyme Inhibitor SHP-141: Acylation of Methyl Paraben and Suberyl Hydroxamic Acid Formation. Org. Process Res. Dev. 2016, 20, 10, 1812-1820.