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69123-54-2

69123-54-2 structure
69123-54-2 structure
  • Name: 3-(4-methylphenyl)-1-(1,3-thiazol-2-yl)urea
  • Chemical Name: 1-(4-methylphenyl)-3-(1,3-thiazol-2-yl)urea
  • CAS Number: 69123-54-2
  • Molecular Formula: C11H11N3OS
  • Molecular Weight: 233.29000
  • Create Date: 2017-06-04 20:49:29
  • Modify Date: 2024-01-28 09:53:09
  • Anticancer agent 38 (compound 19), a sulfonylurea derivative, is a potent anticancer agent. Anticancer agent 38 inhibits A431 cell growth with an IC50 of 5.2 µg/mL[1].

Name 1-(4-methylphenyl)-3-(1,3-thiazol-2-yl)urea
Synonyms 1-thiazol-2-yl-3-(4-methylphenyl)urea
1-thiazol-2-yl-3-p-tolyl-urea
Description Anticancer agent 38 (compound 19), a sulfonylurea derivative, is a potent anticancer agent. Anticancer agent 38 inhibits A431 cell growth with an IC50 of 5.2 µg/mL[1].
Related Catalog
References

[1]. Farid M. Sroor, et al. Anticancer and antimicrobial activities of new thiazolyl-urea derivatives: gene expression, DNA damage, DNA fragmentation and SAR studies. Medicinal Chemistry Research volume 31, pages400–415 (2022).

Density 1.381g/cm3
Molecular Formula C11H11N3OS
Molecular Weight 233.29000
Exact Mass 233.06200
PSA 82.26000
LogP 3.24150
Index of Refraction 1.715
HS Code 2934100090

~67%

69123-54-2 structure

69123-54-2

Literature: Azam, Faizul; Shrivastava, Anil Kumar; Mohan, Govind; Prasad, Medapati Vijaya Vara; Thangavel, Neelaveni Medicinal Chemistry, 2012 , vol. 8, # 6 p. 1057 - 1068,12 Title/Abstract Full Text Show Details Azam, Faizul; Prasad, Medapati Vijaya Vara; Thangavel, Neelaveni; Shrivastava, Anil Kumar; Mohan, Govind Medicinal Chemistry, 2012 , vol. 8, # 6 p. 1057 - 1068
Precursor  2

DownStream  0

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%