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28845-86-5

28845-86-5 structure
28845-86-5 structure
  • Name: Docosatrienoic acid
  • Chemical Name: (13Z,16Z,19Z)-docosatrienoic acid
  • CAS Number: 28845-86-5
  • Molecular Formula: C22H38O2
  • Molecular Weight: 334.536
  • Catalog: Natural Products Others
  • Create Date: 2019-01-02 19:04:14
  • Modify Date: 2024-01-09 14:15:43
  • Docosatrienoic acid is a rare ω-3 fatty acid; inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM.

Name (13Z,16Z,19Z)-docosatrienoic acid
Synonyms 13,16,19-Docosatrienoic acid, (13E,16E,19E)-
13Z,16Z,19Z-DOCOSATRIENOIC ACID
Cis,cis,cis
13C,16C,19C-DOCOSATRIENOIC ACID
CIS-13,16,19-DOCOSATRIENOIC ACID
Cis,cis,cis-13,16,19-Docosatrienoic
Docosa-13Z,16Z,19Z-trienoic acid,22:3,N-3
(13E,16E,19E)-13,16,19-Docosatrienoic acid
13-cis,16-cis,19-cis-Docosatrienoic acid
DOCOSATRIENOIC ACID
DOCOSA-13Z,16Z,19Z-TRIENOIC ACID
Description Docosatrienoic acid is a rare ω-3 fatty acid; inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Docosatrienoic acid inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM[1].
In Vivo Application of docosatrienic acid dose-dependently decreases the peak K+ current amplitide and accelerates the potassium activation and inactivation kinetics at all rat membrane potentials[2].
References

[1]. Yagaloff KA, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids. 1995 May;52(5):293-7.

[2]. Krutetskaia ZI, et al. The effect of docosatrienoic acid on the potassium channels of outward rectification in the membrane of rat peritoneal macrophages. Fiziol Zh Im I M Sechenova. 1995 Jul;81(7):111-9.

Density 0.9±0.1 g/cm3
Boiling Point 459.1±14.0 °C at 760 mmHg
Molecular Formula C22H38O2
Molecular Weight 334.536
Flash Point 355.8±15.2 °C
Exact Mass 334.287170
PSA 37.30000
LogP 8.63
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.488
Storage condition 2-8℃