DC Chemicals Limited
China
Product Name: N-trifluoroacetyl-β-alanyl chloride
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

87639-76-7

87639-76-7 structure

87639-76-7 structure

Name: N-trifluoroacetyl-β-alanyl chloride
Chemical Name: 3-[(2,2,2-trifluoroacetyl)amino]propanoyl chloride
CAS Number: 87639-76-7
Molecular Formula: C₅H₅ClF₃NO₂
Molecular Weight: 203.54700
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2016-05-28 20:09:06
Modify Date: 2024-01-09 16:27:29
N-trifluoroacetyl-β-alanyl chloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	3-[(2,2,2-trifluoroacetyl)amino]propanoyl chloride
Synonyms	Propanoyl chloride,3-[(trifluoroacetyl)amino]

Description	N-trifluoroacetyl-β-alanyl chloride is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Molecular Formula	C₅H₅ClF₃NO₂
Molecular Weight	203.54700
Exact Mass	202.99600
PSA	49.66000
LogP	1.66070

50632-82-1 structure

50632-82-1

~98%

87639-76-7 structure

87639-76-7

Literature: Gani, David; Young, Douglas W. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1355 - 1362

Precursor 1
50632-82-1
DownStream 2
87639-77-8 87639-83-6