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99759-48-5

99759-48-5 structure
99759-48-5 structure

Name 6-Benzoylheteratisine
Synonyms Tri-O-acetylhesperetin
heteratizine
(S)-5,7-diacetoxy-2-(3-acetoxy-4-methoxy-phenyl)-chroman-4-one
O-benzoylheteratisine
benzoylheteratisine
Hesperetin Triacetate
(S)-5,7-Bis(acetyloxy)-2-[3-(acetyloxy)-4-methoxyphenyl]-2,3-dihydro-4H-1-benzopyran-4-one
Description 6-Benzoylheteratisine is a naturally occurring antagonist of the Na+ channel activator aconitine[1].
Related Catalog
In Vitro 6-Benzoylheteratisine (3 μM) decreases the amplitude of the presynaptic fiber spike at all stimulus intensities tested and shiftes the curve to the right[1]. 6-benzoylheteratisine is capable of inhibiting stimulus-triggered epileptiform activity recorded in CA1 stratum pyramidale[1].
References

[1]. A Ameri, et al. Interaction of the structurally related aconitum alkaloids, aconitine and 6-benzyolheteratisine, in the rat hippocampus. Eur J Pharmacol. 1999 Dec 15;386(2-3):187-94.

Density 1.32g/cm3
Boiling Point 645.9ºC at 760 mmHg
Molecular Formula C29H37NO6
Molecular Weight 495.60700
Flash Point 344.4ºC
Exact Mass 495.26200
PSA 85.30000
LogP 2.98790
Index of Refraction 1.622
Storage condition 2-8℃