DC Chemicals Limited
China
Product Name: Cariporide Mesylate
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

159138-81-5

159138-81-5 structure

Name: Cariporide Mesylate
Chemical Name: N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide,methanesulfonic acid
CAS Number: 159138-81-5
Molecular Formula: C₁₃H₂₁N₃O₆S₂
Molecular Weight: 379.45200
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2018-07-23 09:22:07
Modify Date: 2025-08-26 17:13:51
Cariporide is a Na+/H+ Exchanger 1 (NHE-1) inhibitor. Cariporide inhibits the expression of monocyte endothelial cell adhesion and intercellular adhesion molecule-1 (ICAM-1) mediated by high glucose (HG) by inhibiting the activation of NHE-1[1].

Name	N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide,methanesulfonic acid
Synonyms	4-isopropyl-3-methylsulfonylbenzoylguanidine methanesulfonate Cariporide mesylate Cariporide mesilate Cariporide mesylate (USAN)

Description	Cariporide is a Na+/H+ Exchanger 1 (NHE-1) inhibitor. Cariporide inhibits the expression of monocyte endothelial cell adhesion and intercellular adhesion molecule-1 (ICAM-1) mediated by high glucose (HG) by inhibiting the activation of NHE-1[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References	[1]. Wang SX, et al. Cariporide inhibits high glucose-mediated adhesion of monocyte-endothelial cell and expression of intercellular adhesion molecule-1. Life Sci. 2006 Aug 29;79(14):1399-404.

Boiling Point	542.8ºC at 760mmHg
Molecular Formula	C₁₃H₂₁N₃O₆S₂
Molecular Weight	379.45200
Flash Point	282.1ºC
Exact Mass	379.08700
PSA	187.73000
LogP	3.87720
Vapour Pressure	7.62E-12mmHg at 25°C

75-75-2

159138-80-4

~77%

159138-81-5

Literature: Weichert, Andreas; Faber, Sabine; Jansen, Hans W.; Scholz, Wolfgang; Lang, Hans J. Arzneimittel-Forschung/Drug Research, 1997 , vol. 47, # 11 p. 1204 - 1207

154117-61-0

159138-81-5

Literature: Weichert, Andreas; Faber, Sabine; Jansen, Hans W.; Scholz, Wolfgang; Lang, Hans J. Arzneimittel-Forschung/Drug Research, 1997 , vol. 47, # 11 p. 1204 - 1207

176107-23-6

159138-81-5

Literature: Weichert, Andreas; Faber, Sabine; Jansen, Hans W.; Scholz, Wolfgang; Lang, Hans J. Arzneimittel-Forschung/Drug Research, 1997 , vol. 47, # 11 p. 1204 - 1207

Precursor 4
75-75-2 159138-80-4 154117-61-0 176107-23-6
DownStream 0

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