159138-81-5
159138-81-5 structure
- Name: Cariporide Mesylate
- Chemical Name: N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide,methanesulfonic acid
- CAS Number: 159138-81-5
- Molecular Formula: C13H21N3O6S2
- Molecular Weight: 379.45200
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
- Create Date: 2018-07-23 09:22:07
- Modify Date: 2024-01-22 09:35:21
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Cariporide is a Na+/H+ Exchanger 1 (NHE-1) inhibitor. Cariporide inhibits the expression of monocyte endothelial cell adhesion and intercellular adhesion molecule-1 (ICAM-1) mediated by high glucose (HG) by inhibiting the activation of NHE-1[1].
| Name | N-(diaminomethylidene)-3-methylsulfonyl-4-propan-2-ylbenzamide,methanesulfonic acid |
|---|---|
| Synonyms |
4-isopropyl-3-methylsulfonylbenzoylguanidine methanesulfonate
Cariporide mesylate Cariporide mesilate Cariporide mesylate (USAN) |
| Description | Cariporide is a Na+/H+ Exchanger 1 (NHE-1) inhibitor. Cariporide inhibits the expression of monocyte endothelial cell adhesion and intercellular adhesion molecule-1 (ICAM-1) mediated by high glucose (HG) by inhibiting the activation of NHE-1[1]. |
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| Related Catalog | |
| References |
| Boiling Point | 542.8ºC at 760mmHg |
|---|---|
| Molecular Formula | C13H21N3O6S2 |
| Molecular Weight | 379.45200 |
| Flash Point | 282.1ºC |
| Exact Mass | 379.08700 |
| PSA | 187.73000 |
| LogP | 3.87720 |
| Vapour Pressure | 7.62E-12mmHg at 25°C |
|
~77%
159138-81-5 |
| Literature: Weichert, Andreas; Faber, Sabine; Jansen, Hans W.; Scholz, Wolfgang; Lang, Hans J. Arzneimittel-Forschung/Drug Research, 1997 , vol. 47, # 11 p. 1204 - 1207 |
|
~%
159138-81-5 |
| Literature: Weichert, Andreas; Faber, Sabine; Jansen, Hans W.; Scholz, Wolfgang; Lang, Hans J. Arzneimittel-Forschung/Drug Research, 1997 , vol. 47, # 11 p. 1204 - 1207 |
|
~%
159138-81-5 |
| Literature: Weichert, Andreas; Faber, Sabine; Jansen, Hans W.; Scholz, Wolfgang; Lang, Hans J. Arzneimittel-Forschung/Drug Research, 1997 , vol. 47, # 11 p. 1204 - 1207 |
| Precursor 4 | |
|---|---|
| DownStream 0 | |