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157528-81-9

157528-81-9 structure
157528-81-9 structure
  • Name: Coronarin D methyl ether
  • Chemical Name: (3E)-5-Methoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedec ahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone
  • CAS Number: 157528-81-9
  • Molecular Formula: C21H32O3
  • Molecular Weight: 332.48
  • Catalog: Natural product Moss
  • Create Date: 2017-03-14 22:59:33
  • Modify Date: 2024-01-12 10:03:01

Name (3E)-5-Methoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedec ahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone
Synonyms (3E)-5-Methoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone
2(3H)-Furanone, 3-[2-[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-5-methoxy-, (3E)-
(3Z)-5-Methoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone
2(3H)-Furanone, 3-[2-[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-5-methoxy-, (3Z)-
Description Methoxycoronarin D can be isolated from Hedychium coronarium J. Koenig and is a potent inhibitor of NF-魏B with an IC50 value of 7.3 渭M. Methoxycoronarin D is also a selective inhibitor of COX-1 with an IC50 value of 0.9 渭M[1].
Related Catalog
References

[1]. Endringer D C, et al. Cancer chemoprevention activity of labdane diterpenes from rhizomes of Hedychium coronarium[J]. Revista Brasileira de Farmacognosia, 2014, 24: 408-412.

Density 1.0±0.1 g/cm3
Boiling Point 447.8±45.0 °C at 760 mmHg
Molecular Formula C21H32O3
Molecular Weight 332.48
Flash Point 191.7±23.3 °C
Exact Mass 332.235138
PSA 35.53000
LogP 5.65
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.516
Hazard Codes Xi