115616-51-8
115616-51-8 structure
- Name: PDPH Crosslinker
- Chemical Name: 3-(pyridin-2-yldisulfanyl)propanehydrazide
- CAS Number: 115616-51-8
- Molecular Formula: C8H11N3OS2
- Molecular Weight: 229.32200
- Create Date: 2017-08-04 14:15:12
- Modify Date: 2025-08-25 09:34:21
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PDPH Crosslinker, or SPDP Hydrazide, is a cleavable, heterobifunctional protein crosslinker. PDPH crosslinking reagent's hydrazide group selectively reacts with oxidized carbohydrates (or carboxyls when used with EDC); while the pyridinyldisulfide moity is reactive toward reduced thiols (sulfhydryls; -SH). Thus, PDPH linker is an excellent choice for crosslinking glycoproteins and other polysaccharides.
| Name | 3-(pyridin-2-yldisulfanyl)propanehydrazide |
|---|---|
| Synonyms |
TPMPH
PDTPA-Hydrazide |
| Density | 1.35g/cm3 |
|---|---|
| Boiling Point | 463.6ºC at 760mmHg |
| Melting Point | 87-90ºC |
| Molecular Formula | C8H11N3OS2 |
| Molecular Weight | 229.32200 |
| Flash Point | 234.2ºC |
| Exact Mass | 229.03400 |
| PSA | 118.61000 |
| LogP | 2.29310 |
| Vapour Pressure | 8.98E-09mmHg at 25°C |
| Index of Refraction | 1.652 |
| Hazard Codes | Xn |
|---|
|
~48%
115616-51-8 |
| Literature: NeoRx Corporation Patent: US5608060 A1, 1997 ; |
| Precursor 1 | |
|---|---|
| DownStream 1 | |