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5688-80-2

5688-80-2 structure
5688-80-2 structure
  • Name: UNII:B6B7TX22VO
  • Chemical Name: 1-(3,4,5-trimethoxyphenyl)propan-2-amine,hydrochloride
  • CAS Number: 5688-80-2
  • Molecular Formula: C12H20ClNO3
  • Molecular Weight: 261.745
  • Create Date: 2016-09-14 05:07:05
  • Modify Date: 2025-08-27 21:05:44
  • 3,4,5-Trimethoxyamphetamine (TMA), is a psychedelic hallucinogen that has appeared on the illicit drug market.

Name 1-(3,4,5-trimethoxyphenyl)propan-2-amine,hydrochloride
Synonyms Phenethylamine, 3,4,5-trimethoxy-α-methyl-, hydrochloride (8CI)
Benzeneethanamine, 3,4,5-trimethoxy-α-methyl-, hydrochloride (9CI)
Benzeneethanamine, 3,4,5-trimethoxy-α-methyl-, hydrochloride
1-(3,4,5-Trimethoxyphenyl)propan-2-amine hydrochloride (1:1)
Phenethylamine, 3,4,5-trimethoxy-α-methyl-, hydrochloride
Phenethylamine, α-methyl-3,4,5-trimethoxy-, hydrochloride
Benzeneethanamine, 3,4,5-trimethoxy-α-methyl-, hydrochloride (1:1)
1-(3,4,5-Trimethoxyphenyl)-2-propanamine hydrochloride (1:1)
UNII:B6B7TX22VO
Density 1.048g/cm3
Boiling Point 321.7ºC at 760 mmHg
Molecular Formula C12H20ClNO3
Molecular Weight 261.745
Flash Point 148.6ºC
Exact Mass 261.113159
PSA 53.71000
LogP 3.10440

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SI2285000
CHEMICAL NAME :
Phenethylamine, alpha-methyl-3,4,5-trimethoxy-, hydrochloride
CAS REGISTRY NUMBER :
5688-80-2
LAST UPDATED :
198910
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C12-H19-N-O3.Cl-H
MOLECULAR WEIGHT :
261.78
WISWESSER LINE NOTATION :
Z1Y1&R CO1 DO1 EO1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
880 ug/kg
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions Behavioral - changes in motor activity (specific assay) Gastrointestinal - nausea or vomiting
REFERENCE :
JMSCA9 Journal of Mental Science. (London, UK) V.4-108, 1857-1962. For publisher information, see BJPYAJ. Volume(issue)/page/year: 101,317,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
149 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
240 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
23 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Gastrointestinal - nausea or vomiting
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
31 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - nausea or vomiting
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
172 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,299,1973
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