254877-04-8
254877-04-8 structure
- Name: S-3448
- Chemical Name: 2-[(4-chlorophenyl)sulfonylamino]-4,5-dimethoxy-N-(4-thiomorpholin-4-ylsulfonylphenyl)benzamide
- CAS Number: 254877-04-8
- Molecular Formula: C25H25ClN2O8S3
- Molecular Weight: 613.12300
- Create Date: 2017-04-26 18:52:17
- Modify Date: 2025-09-22 14:38:23
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S-3448 is a potent, specific soluble guanylate cyclase (sGC) activator with EC50 of 0.68 uM, preferentially activates the NO-insensitive heme-oxidized form of sGC.
| Name | 2-[(4-chlorophenyl)sulfonylamino]-4,5-dimethoxy-N-(4-thiomorpholin-4-ylsulfonylphenyl)benzamide |
|---|---|
| Synonyms |
2-[[(4-chlorophenyl)sulfonyl]amino]-4,5-dimethoxy-n-[4-(4-thiomorpholinylsulfonyl)phenyl]benzamide
s-3448 |
| Density | 1.485g/cm3 |
|---|---|
| Molecular Formula | C25H25ClN2O8S3 |
| Molecular Weight | 613.12300 |
| Exact Mass | 612.04600 |
| PSA | 179.16000 |
| LogP | 6.58110 |
| Index of Refraction | 1.658 |