Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: methopromazine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

61-01-8

61-01-8 structure

Name: methopromazine
Chemical Name: 3-(2-methoxyphenothiazin-10-yl)-N,N-dimethylpropan-1-amine
CAS Number: 61-01-8
Molecular Formula: C₁₈H₂₂N₂OS
Molecular Weight: 314.44500
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyrimidine compound Ketones
Create Date: 2018-09-25 12:32:12
Modify Date: 2025-08-25 15:17:01

Name	3-(2-methoxyphenothiazin-10-yl)-N,N-dimethylpropan-1-amine
Synonyms	2-Methoxypromazine Methopromazinum [INN-Latin] Neoproma [3-(2-methoxy-phenothiazin-10-yl)-propyl]-dimethyl-amine RP 4632 Methoxypromazine Tentone 2-Methoxy-10-(3'-dimethylaminopropyl)phenothiazine Methopromazine Tenton Methopromazin Metopromazina [INN-Spanish] Levopromazine [3-(2-Methoxy-phenothiazin-10-yl)-propyl]-dimethyl-amin

Density	1.143g/cm3
Boiling Point	461.8ºC at 760 mmHg
Molecular Formula	C₁₈H₂₂N₂OS
Molecular Weight	314.44500
Flash Point	233.1ºC
Exact Mass	314.14500
PSA	41.01000
LogP	4.31460
Index of Refraction	1.603

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SO7600000

CHEMICAL NAME :: Phenothiazine, 10-(3-(dimethylamino)propyl)-2-methoxy

CAS REGISTRY NUMBER :: 61-01-8

LAST UPDATED :: 198209

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C18-H22-N2-O-S

MOLECULAR WEIGHT :: 314.48

WISWESSER LINE NOTATION :: T C666 BN ISJ B3N1&1 EO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 730 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 125,101,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 95 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 125,101,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 408 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 125,101,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 112 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 125,101,1960 *** REVIEWS *** TOXICOLOGY REVIEW JMSCA9 Journal of Mental Science. (London, UK) V.4-108, 1857-1962. For publisher information, see BJPYAJ. Volume(issue)/page/year: 106,755,1960

1771-18-2

109-54-6

61-01-8

Literature: Soc. Usines Chim. Rhone-Poulenc Patent: US2785160 , 1952 ; Full Text Show Details Soc. Usines Chim. Rhone-Poulenc Patent: DE940829 , 1952 ;

107627-98-5

61-01-8

Literature: Soc. Usines Chim. Rhone-Poulenc Patent: US2769002 , 1954 ;

67-56-1

69-09-0

~0%

61-01-8

53-60-1

Literature: Garcia, Carmelo; Pinero, Luis; Oyola, Rolando; Arce, Rafael Photochemistry and Photobiology, 2009 , vol. 85, # 1 p. 160 - 170

Precursor 5
1771-18-2 109-54-6 107627-98-5 67-56-1
69-09-0
DownStream 0

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