Nanjing Peptide Biotech Ltd
China
Product Name: Dihydro Cyclosporin A
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: DIHYDROCYCLOSPORIN A
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

59865-15-5

59865-15-5 structure

59865-15-5 structure

Name: Dihydro Cyclosporin A
Chemical Name: Dihydro Cyclosporin A
CAS Number: 59865-15-5
Molecular Formula: C₆₂H₁₁₃N₁₁O₁₂
Molecular Weight: 1204.627
Catalog: Research Areas Infection
Create Date: 2018-03-02 08:00:00
Modify Date: 2024-01-20 12:01:16
Dihydrocyclosporin A is a derivative of Cyclosporine A (HY-B0579). Dihydrocyclosporin A significantly inhibites promastigotes and intracellular amastigotes. Dihydrocyclosporin A is highly cytotoxic[1].

Name	Dihydro Cyclosporin A
Synonyms	6-[(2S,3R,4R)-3-Hydroxy-4-Methyl-2-(MethylaMino)octanoic acid]cyclosporin A <DH-MeBmt>cyclosporin dihydro-CSA DIHYDROCYCLOSPORIN A Dihydrocyclosporin (3S,6S,9S,12R,15S,18S,21S,24S,30S)-30-Ethyl-33-[(1R,2R)-1-hydroxy-2-methylhexyl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone (3R,4R)-3-Hydroxy-N-methyl-5-propylcyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-) (3R,4R)-3-Hydroxy-4,N-dimethyl-5-propylcyclo[L-Nva-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-] 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 30-ethyl-33-[(1R,2R)-1-hydroxy-2-methylhexyl]-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S,6S,9S,12R,15S,18S,21S,24S,30S)- Cyclosporin Impurity 10

Description	Dihydrocyclosporin A is a derivative of Cyclosporine A (HY-B0579). Dihydrocyclosporin A significantly inhibites promastigotes and intracellular amastigotes. Dihydrocyclosporin A is highly cytotoxic[1].
Related Catalog	Research Areas >> Infection
References	[1]. Zheng ZW, et al. Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosuppressive derivative, dihydrocyclosporin A. Parasit Vectors. 2020 Feb 21;13(1):94.

Density	1.0±0.1 g/cm3
Boiling Point	1285.3±65.0 °C at 760 mmHg
Melting Point	120-125ºC
Molecular Formula	C₆₂H₁₁₃N₁₁O₁₂
Molecular Weight	1204.627
Flash Point	731.1±34.3 °C
Exact Mass	1203.857056
PSA	278.80000
LogP	3.67
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.465
Storage condition	-20°C

Precursor 3
59865-13-3 121584-52-9 83563-94-4
DownStream 0