CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
VV3540000
-
CHEMICAL NAME :
-
Silane, (dichlorophenyl)trichloro-
-
CAS REGISTRY NUMBER :
-
27137-85-5
-
LAST UPDATED :
-
199701
-
DATA ITEMS CITED :
-
10
-
MOLECULAR FORMULA :
-
C6-H3-Cl5-Si
-
MOLECULAR WEIGHT :
-
280.43
-
WISWESSER LINE NOTATION :
-
G-SI-GGR XG XG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LCLo - Lowest published lethal concentration
-
ROUTE OF EXPOSURE :
-
Inhalation
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
80 mg/m3/2H
-
TOXIC EFFECTS :
-
Brain and Coverings - changes in circulation (hemorrhage, thrombosis, etc.) Lungs, Thorax, or Respiration - acute pulmonary edema Blood - hemorrhage
-
REFERENCE :
-
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 3,48,1961
-
TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
100 mg/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
REFERENCE :
-
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 3,81,1961
-
TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
100 mg/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
REFERENCE :
-
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,48,1982
-
TYPE OF TEST :
-
LCLo - Lowest published lethal concentration
-
ROUTE OF EXPOSURE :
-
Inhalation
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
80 mg/m3/2H
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
REFERENCE :
-
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,48,1982
-
TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
100 mg/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
REFERENCE :
-
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 3,81,1961
-
TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
100 mg/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
REFERENCE :
-
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 3,81,1961
-
TYPE OF TEST :
-
LC50 - Lethal concentration, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Inhalation
-
SPECIES OBSERVED :
-
Mammal - species unspecified
-
DOSE/DURATION :
-
40 mg/m3
-
TOXIC EFFECTS :
-
Lungs, Thorax, or Respiration - acute pulmonary edema Liver - fatty liver degeneration Blood - other changes
-
REFERENCE :
-
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 3,81,1961 ** OTHER MULTIPLE DOSE TOXICITY DATA **
-
TYPE OF TEST :
-
TCLo - Lowest published toxic concentration
-
ROUTE OF EXPOSURE :
-
Inhalation
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
20 mg/m3/3H/11W-I
-
TOXIC EFFECTS :
-
Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Related to Chronic Data - death
-
REFERENCE :
-
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 3,48,1961
-
TYPE OF TEST :
-
TCLo - Lowest published toxic concentration
-
ROUTE OF EXPOSURE :
-
Inhalation
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
9 mg/m3/3H/35W-I
-
TOXIC EFFECTS :
-
Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - emphysema Nutritional and Gross Metabolic - weight loss or decreased weight gain
-
REFERENCE :
-
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 3,48,1961
|
