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22748-16-9

22748-16-9 structure
22748-16-9 structure
  • Name: 4,4-Dimethyl-2-cyclopenten-1-one
  • Chemical Name: 4,4-dimethylcyclopent-2-en-1-one
  • CAS Number: 22748-16-9
  • Molecular Formula: C7H10O
  • Molecular Weight: 110.15400
  • Catalog: Signaling Pathways Others Others
  • Create Date: 2018-12-04 19:07:55
  • Modify Date: 2024-01-05 17:43:44
  • 4,4-Dimethyl-2-cyclopenten-1-one, a natural compound from Apocyniveneti Folium, displays higher tumor-specific cytotoxicity[1].

Name 4,4-dimethylcyclopent-2-en-1-one
Synonyms 4,4-dimethyl-2-cyclopentenone
4,4-dimethyl-2-cyclopenten-1-one
4,4-dimethylcyclopent-2-enone
4,4-Dimethylcyclopent-2-en-1-on
MFCD00075081
4,4-Dimethylcyclopent-2-ene-1-one
Description 4,4-Dimethyl-2-cyclopenten-1-one, a natural compound from Apocyniveneti Folium, displays higher tumor-specific cytotoxicity[1].
Related Catalog
In Vitro 4,4-Dimethyl-2-cyclopenten-1-one selectively kills the tumor cells (HSC-2, HL-60). 4,4-Dimethyl-2-cyclopenten-1-one exhibits CC50 (50% cytotoxic concentration) values of 43.8 μg/mL, 152 μg/mL, 118 μg/mL, 14.0 μg/mL, 177 μg/mL and 123 μg/mL in HSC-2, HSC-3, HSG, HL-60, HGF and normal cells (HPC), respectively[1].
References

[1]. Tohru Nakayachi, et al. Structure-activity relationships of alpha, beta-unsaturated ketones as assessed by their cytotoxicity against oral tumor cells. Anticancer Res. Mar-Apr 2004;24(2B):737-42.

[2]. Wei-WeiZhu, et al. Cornstalk liquefaction in methanol/water mixed solvents. Fuel Processing Technology Volume 117, January 2014, Pages 1-7.

Density 0.903
Boiling Point 155.1ºC at 760mmHg
Melting Point 174-175 °C
Molecular Formula C7H10O
Molecular Weight 110.15400
Flash Point 46ºC
Exact Mass 110.07300
PSA 17.07000
LogP 1.54160
Vapour Pressure 3.09mmHg at 25°C
Index of Refraction 1.457
Storage condition 2-8°C
Symbol GHS02
GHS02
Signal Word Warning
Hazard Statements H226
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Risk Phrases R10
Safety Phrases 16
RIDADR UN 1224
Packaging Group III
Hazard Class 3.2
HS Code 2914299000
HS Code 2914299000
Summary 2914299000. other cyclanic, cyclenic or cyclotherpenic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%