- DC Chemicals Limited
- China
- Product Name: Minoxidil sulfate
- Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Minoxidil sulphate
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Minoxidil sulphate
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Minoxidil Sulfate
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
83701-22-8
83701-22-8 structure
- Name: Minoxidil sulphate
- Chemical Name: Minoxidil Sulfate
- CAS Number: 83701-22-8
- Molecular Formula: C9H15N5O4S
- Molecular Weight: 289.311
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
- Create Date: 2018-05-26 08:00:00
- Modify Date: 2024-01-03 20:57:49
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Minoxidil sulfate, a potent and ATP-sensitive K+ channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in vivo[1][3].
| Name | Minoxidil Sulfate |
|---|---|
| Synonyms |
({[2,6-Diamino-4-(1-piperidinyl)pyrimidin-1-ium-1-yl]oxy}sulfonyl)oxidanide
Pyrimidinium, 2,6-diamino-4-(1-piperidinyl)-1-(sulfooxy)-, inner salt (2,6-diamino-4-piperidin-1-ylpyrimidin-1-ium-1-yl) sulfate MFCD06248907 Minoxidil sulphate |
| Description | Minoxidil sulfate, a potent and ATP-sensitive K+ channel opener, is the sulfated metabolite of minoxidil. Minoxidil sulfate is considered as a vasodilator to promote hair growth in vivo[1][3]. |
|---|---|
| Related Catalog | |
| Target |
IC50: K channel[2] |
| In Vitro | Minoxidil sulfate (1-100 μM; 2 hours) significantly reduces the permeability of bloode-brain tumor barrier (BTB) in a monolayer of RBMEC in a time-dependent manner, additionally,the effects of MS on transendothelial electrical resistance (TEER) is Transendothelial electrical resistance (TEER) at 2 h with high concentration[2]. Minoxidil sulfate (0-100 μM; 0-4 hours) increases the RhoA activation in brain tumor tissue by 1 h and the highest level appears at 2 h, it also significantly induces transient PKB phosphorylation at Ser-473, without affecting total PKB levels. Addiotionally, LY294002 partly prevents the phosphorylation of PKB induced by MS[2]. Western Blot Analysis[2] Cell Line: Rat brain microvascular endothelial cells (RBMECs) Concentration: 0-100 μM Incubation Time: 15 mins, 30 mins, 1 hour, 2 hours, 4 hours Result: Induced RhoA activation and PKB phosphorylation at Ser-473. |
| References |
| Boiling Point | 732ºC at 760 mmHg |
|---|---|
| Melting Point | 175-180°C |
| Molecular Formula | C9H15N5O4S |
| Molecular Weight | 289.311 |
| Flash Point | 396.5ºC |
| Exact Mass | 289.084473 |
| PSA | 146.86000 |
| LogP | 0.72080 |
| Storage condition | −20°C |
| Stability | Light Sensitive - Protect from Light, Store in Freezer |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R22;R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2933599090 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |