98320-39-9

98320-39-9 structure

98320-39-9 structure

Name: IX 207-887
Chemical Name: Acetic acid, 2-(10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)
CAS Number: 98320-39-9
Molecular Formula: C₁₆H₁₂O₃S
Molecular Weight: 284.33000
Catalog: Signaling Pathways Immunology/Inflammation Interleukin Related
Create Date: 2017-07-25 08:14:46
Modify Date: 2024-01-02 18:35:32
IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).

Name	Acetic acid, 2-(10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)
Synonyms	IX 207887 4H-Benzo[4,5]cyclohepta[1,2-b]thiophene, acetic acid deriv. (Z)-10-METHOXY-4H-BENZO[4,5]CYCLOHEPTA[1,2-B]THIOPHENE-4-YLIDENE ACETIC ACID Acetic acid, (10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)- IX 207-887

Description	IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology
Target	Interleukin-1[1]
In Vitro	IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed[1].
References	[1]. Schnyder J, et al. Inhibition of interleukin-1 release by IX 207-887. Agents Actions. 1990 Jun;30(3-4):350-62.

Molecular Formula	C₁₆H₁₂O₃S
Molecular Weight	284.33000
Exact Mass	284.05100
PSA	74.77000
LogP	3.72230

HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%