34209-69-3

34209-69-3 structure

Name: Trachelogenin
Chemical Name: (3S,4S)-4-[(3,4-dimethoxyphenyl)methyl]-3-hydroxy-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
CAS Number: 34209-69-3
Molecular Formula: C₂₁H₂₄O₇
Molecular Weight: 388.41100
Catalog: Signaling Pathways Anti-infection HCV
Create Date: 2016-12-26 04:38:25
Modify Date: 2024-01-05 00:24:48
Trachelogenin ((-)-Trachelogenin) is an HCV entry inhibitor without genotype specificity, and with low cytotoxicity. Trachelogenin inhibits HCVcc infection and HCVpp cell entry in a dose-dependent manner with an IC50 of 0.325 and 0.259 μg/mL in HCVcc and HCVpp models, respectively. Trachelogenin exhibits effective antiviral, anti-inflammatory and analgesic effects[1].

Name	(3S,4S)-4-[(3,4-dimethoxyphenyl)methyl]-3-hydroxy-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
Synonyms	Trachelogenin (-)-Trachelogenin

Description	Trachelogenin ((-)-Trachelogenin) is an HCV entry inhibitor without genotype specificity, and with low cytotoxicity. Trachelogenin inhibits HCVcc infection and HCVpp cell entry in a dose-dependent manner with an IC50 of 0.325 and 0.259 μg/mL in HCVcc and HCVpp models, respectively. Trachelogenin exhibits effective antiviral, anti-inflammatory and analgesic effects[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HCV Research Areas >> Infection Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. Xi-Jing Qian, et al. Trachelogenin, a novel inhibitor of hepatitis C virus entry through CD81. J Gen Virol. 2016 May;97(5):1134-1144.